Publications

2019

• Yang W, Rosenstiel P, Schulenburg H:
  aFold - using polynomial uncertainty modelling for differential gene expression estimation from RNA sequencing data.
  BMC Genomics 20(1):364, doi: 10.1186/s12864-019-5686-1
  
  
• Mohamad Jawhara, Signe Bek Sørensen, Berit Lilienthal Heitmann, and Vibeke Andersen:
  Biomarkers of Whole-Grain and Cereal-Fiber Intake in Human Studies: A Systematic Review of the Available Evidence and Perspectives
  Nutrients, 10.3390/nu11122994
  
  
• Rosati E, Pogorelyy MV, Dowds CM, Moller FT, Sorensen SB, Lebedev YB, Frey N, Schreiber S, Spehlmann ME, Andersen V, Mamedov IZ, Franke A.:
  Identification of disease-associated traits and clonotypes in the T-cell receptor repertoire of monozygotic twins affected by inflammatory bowel diseases.
  J Crohns Colitis, doi: 10.1093/ecco-jcc/jjz179
  
  
• Alyce C. Russell, Agnieszka Kepka, Irena Trbojević-Akmačić, Ivo Ugrina, Manshu Song, Jennie Hui, Michael Hunter, Simon M. Laws, Gordan Lauc, Wei Wang:
  Increased central adiposity is associated with pro-inflammatory immunoglobulin G N-glycans.
  Immunobiology Volume 224, Issue 1, January 2019, 110-115, 10.1016/j.imbio.2018.10.002
  
  

2018

• Aden K, Tran F, Ito G, Sheibani-Tezerji R, Lipinski S, Kuiper JW, Tschurtschenthaler M, Saveljeva S, Bhattacharyya J, Hälser R, Barsch K, Luzius A, Jentsch M, Falk-Paulsen M, Stengel ST, Weiz L, Schwarzer R, Rabe B, Barchet W, Krautwald S, Hartmann G, Pasparakis M, Blumbert RS, Schreiber S, Kaser A, Rosenstiel P:
  ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING.
  J Exp Med. 2018 Nov 5;215(11), 2868-2886, doi: 10.1084/jem.20171029
  
  
• Zaghlool SB, Mook-Kanamori DO, Kader S, Stephan N, Halama A, Engelke R, Sarwath H, Al-Dous EK, Mohamoud YA, Roemisch-Markl W, Adamski J, Kastenmüller G, Friedrich N, Visconti A, Tsai PC, Spector T, Bell JT, Falschi M, Wahl A, Waldenberger M, Peters A, Gieger C, Pezer M, Lauc G, Graumann J, Malek JA, Suhre K :
  Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation
  Human Molecular Genetics 27(6): 1106–1121, doi: 10.1093/hmg/ddy006
  
  
• Howell KJ, Kraiczy J, Nayak KM, Gasparetto M, Ross A, Lee C, Mak TN, Koo BK, Kumar N, Lawley T, Sinha A, Rosenstiel P, Heuschkel R, Stegle O, Zilbauer M:
  DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome
  Gastroenterology 154(3):585-598, doi: 10.1053/j.gastro.2017.10.007
  
  
• Nikolaus S, Waetzig GH, Butzin S, Ziolkiewicz M, Al-Massad N, Thieme F, Lövgren U, Rasmussen BB, Reinheimer TM, Seegert D, Rosenstiel P, Szymczak S, Schreiber S:
  Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseases
  J Colorectal Dis 33(7):927-936, doi: 10.1007/s00384-018-3069-8
  
  
• Šimurina M, de Haan N, Vučković F, Kennedy N A, Štambuk J, Falck D, Trbojević-Akmačić I, Clerc F, Razdorov G, Khon A, Latiano A, D'Incà R, Danese S, Targan S, Landers C, Dubinsky M, IBD-BIOM consortium, McGovern D P M, Annese V, Wuhrer M, Gordan L:
  Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases
  Gastroenterology, doi: 10.1053/j.gastro.2018.01.002
  
  
• Momozawa Y, Dmitrieva J, Théâtre E, Deffontaine V, Rahmouni S, Charloteaux B, Crins F, Docampo E, Elansary M, Gori AS, Lecut C, Mariman R, Mni M, Oury C, Altukhov I:
  IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
  Nature Communications 9(1):2427, doi: 10.1038/s41467-018-04365-8
  
  
• Gudelj I, Salo PP, Trbojević-Akmačić I, Albers M, Primorac D, Perola M, Lauc G.:
  Low galactosylation of IgG associates with higher risk for future diagnosis of rheumatoid arthritis during 10 years of follow-up
  Biochimica Biophysica Acta - Molecular Basis of Disease Volume 1864, Issue 6, Part A, June 2018, 2034-2039, doi:10.1016/j.bbadis.2018.03.018
  
  
• Thion MS, Low D; Silvin A, Chen J, Grisel P, Schule Schrepping J, Blecher R, Ulas T, Squarzoni P, Hoeffel G, Coulpier F, Siopi E, David FS, Scholz C, Shihui F, Lum J, Amoyo AA, Larbi A, Poidinger M, Buttgereit A, Liedo PM, Greter M, Chan JKY, Amit I, Beyer M, Schultze JL, Schlitzer A, Pettersson S, Ginhoux F, Garel S:
  Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner
  Cell 172, 25 January 2018, 500-516, doi: 10.1016/j.cell.2017.11.042
  
  
• Kosicek M, Gudelj I, Horvatic A, Jovic T, Vuckovic F, Lauc G, Hecimovic S.:
  N-glycome of the lysosomal glycocalyx is altered in Niemann-Pick Type C disease (NPC) model cells
  Molecular & Cellular Proteomics, 24 January 2018, doi: 10.1074/mcp.RA117.000129
  
  
• Krištić J, Zaytseva OO, Ram R, Nguyen Q, Novokmet M, Vučković F, Vilaj M, Trbojević-Akmačić I, Pezer M, Davern KM, Morahan G, Lauc G.:
  Profiling and genetic control of the murine immunoglobulin G glycome.
  Nature Chemical Biology 14, 09 April 2018, 516–524, doi: 10.1038/s41589-018-0034-3
  
  
• Schultze JL, SYSCID consortium, Rosenstiel P:
  Systems Medicine in Chronic Inflammatory Diseases
  Immunity 48(4), 608-613, doi: 10.1016/j.immuni.2018.03.022
  
  
• Liu JN, Dolikun M, Štambuk J, Trbojević-Akmačić I, Zhang J, Wang H, Zheng DQ, Zhang XY, Peng HL, Zhao ZY, Liu D, Sun Y, Sun Q, Li QH, Zhang JX, Sun M, Cao WJ, Momčilović A, Razdorov G, Wu LJ, Russell A, Wang YX, Song MS, Lauc G, Wang W.:
  The association between subclass-specific IgG Fc N-glycosylation profiles and hypertension in the Uygur, Kazak, Kirgiz, and Tajik populations.
  Journal of Human Hypertension, doi:10.1038/s41371-018-0071-0
  
  
• Zeissig S, Rosati E, Dowds CM, Aden K, Bethge J, Schulte B, Pan WH, Mishra N, Zuhayra M, Marx M, Paulsen M, Strigli A, Conrad C, Schuldt D, Sinha A, Ebsen H, Kornell SC, Nikolaus S, Arlt A, Kabelitz D, Ellrichmann M, Lützen U, Rosenstiel PC, Franke A, Schreiber S:
  Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease
  Gut, 2018 May 5, doi: 10.1136/gutjnl-2018-316023
  
  
• Christ A, Günther P, Lauterbach MAR, Duewell P, Biswas D, Pelka K, Scholz CJ, Oosting M, Haendler K, Baßler K, Klee K, Schulte-Schrepping.J, Ulas T, Moorlag SJCFM, Kumar V, Park MH, Joosten LAB, Groh LA, Riksen NP, Espevik T, Schlitzer A, Li Y, Fitzgerald ML, Netea MG, Schultze JL, Latz E:
  Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming
  Cell 172(1-2), 162-175, doi: 10.1016/j.cell.2017.12.013
  
  

2017

• Andersen V, Holmskov U, Sorensen SB, Jawhara M, Andersen KW, Bygum A, Hvid L, Grauslund J, Wied J, Glerup H, Fredberg U, Villadsen JA, Kjaer SG, Fallingborg J, Moghadd SAGR, Knudsen T, Brodersen J, Frojk J, Dahlerup JF, Nielsen OH, Christensen R, Bojesen AB:
  A proposal for a study on treatment selection and lifestyle recommendations in chronic inflammatory diseases: A Danish multidisciplinary collaboration on prognostic factors and personalised medicine
  Nutrients 9(5),499, 10.3390/nu9050499
  
  
• Andersen K, Christensen R, Heitmann B, Nielsen O, Sørensen S, Jawhara M, Bygum A, Hvid L, Grauslund J, Wied J, Glerup H, Fredberg U, Villadsen J:
  Impact of red and processed meat and fibre intake on treatment outcome among patients with chronic inflammatory diseases: Protocol for a prospective cohort study on prognostic factors and personalised medicine
  BMJ Open
  
  
• Nikolaus S, Schulte B, Al-Massad N, Thieme F, Schulte DM, Bethge J, Rehman A, Tran F, Aden K, Häsler R, Moll N, Schütze G, Schwarz MJ, Waetzig GH, Rosenstiel P, Krawczak M, Szymczak S, Schreiber S.:
  Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases
  Gastroenterology Volume 153, Issue 6, December 2017, Pages 1504-1516, doi: 10.1053/j.gastro.2017.08.028
  
  
• Shen X, Klarić L, Sharapov S, Mangino M, Ning Z, Wu D, Trbojević-Akmačić I, Pučić-Baković M, Rudan I, Polašek O, Hayward C, Spector TD, Wilson JF, Lauc G, Aulchenko YS:
  Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation
  Nature Communications 447, Published online: 06 September 2017, doi: 10.1038/s41467-017-00453-3
  Additional link
  
  
• Rosati E, Dowds CM, Liaskou E, Klemsdal Henriksen EK, Karlsen TH and Franke A:
  Overview of methodologies for T-cell receptor repertoire analysis
  BMC Biotechnology 17:61, doi: 10.1186/s12896-017-0379-9
  
  
• Vandeputte D, Kathagen G, D’hoe K, Vieira-Silva S, Valles-Colomer M, Sabino J, Wang J, Tito R Y, De Commer L, Darzi Y, Vermeire S, Falony G, Raes J:
  Quantitative microbiome profiling links gut community variation to microbial load
  Nature 551 (23 November 2017), 507–511 , doi:10.1038/nature24460
  
  
• Sommer F, Anderson JM, Bharti R, Raes J, Rosenstiel P:
  The resilience of the intestinal microbiota influences health and disease
  Nature Reviews Microbiology 15, 630-638, doi:10.1038/nrmicro.2017.58
  
  
• O'Flaherty R, Trbojević-Akmačić I, Greville G, Rudd PM, Lauc G.:
  The sweet spot for biologics: recent advances in characterization of biotherapeutic glycoproteins.
  Expert Review of Proteomics, doi: 10.1080/14789450.2018.1404907